A Influência do Estresse Psicológico na Progressão e Evolução do HIV: Uma Revisão Sistemática

Carolina Fioravanço da Silva; Karina Kirsten; Carolain Felipin Vincensi Anklam

doi:10.36489/saudecoletiva.2025v16i98p16716-16731

Authors

Carolina Fioravanço da Silva Graduada em Biomedicina pela ATITUS Educação. Auxiliar de laboratório Sênior na AKF imunotech; Passo Fundo; RS. https://orcid.org/0009-0000-1369-9437
Karina Kirsten ATITUS Educação
Carolain Felipin Vincensi Anklam Professora do curso de Biomedicina da Atitus Educação https://orcid.org/0000-0001-6984-7136

DOI:

https://doi.org/10.36489/saudecoletiva.2025v16i98p16716-16731

Keywords:

HIV/AIDS, Stress, Immune system, Systematic review

Abstract

The research was carried out through a systematic review of studies published between 1990 and 2024, using the Pubmed, Science Direct and Scopus databases, with the search terms "HIV/AIDS" AND "stress" AND "immune system". The inclusion criteria were: studies in humans and that evaluated immunological markers and parameters of stress, anxiety and depression. After screening, 15 articles were included in this review. The results show that psychological stress, especially when related to anxiety and depression, negatively affects the immune system, accelerating the progression of HIV infection. However, interventions such as emotional therapy and regular physical activity have been shown to be effective in the homeostasis of the immune system. It is concluded that stress has a direct influence on the progression of the infection by impairing the immune response, the inclusion of psychosocial interventions is essential to improve quality of life and delay the progression of the disease.

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