Risco de Danos em Pediatria: Eventos Adversos Associados ao Uso de Medicamentos

Jamilly Souza Tavares; Gilmara Rodrigues Lima Furlan; Matheus Cade Coelho Soares; Paula Gabrielle Gomes Candido; Wherveson de Araújo Ramos

doi:10.36489/saudecoletiva.2025v16i99p16838-16851

Authors

Jamilly Souza Tavares Discente de Medicina da Faculdade de Ciências Médicas do Pará https://orcid.org/0000-0002-1068-291X
Gilmara Rodrigues Lima Furlan Discente de Medicina da Faculdade de Ciências Médicas do Pará https://orcid.org/0000-0001-6606-2392
Matheus Cade Coelho Soares Discente de Medicina da Faculdade de Ciências Médicas do Pará https://orcid.org/0000-0001-5772-2299
Paula Gabrielle Gomes Candido Enfermeira; Mestre pelo Programa de Pós-Graduação em Saúde e Tecnologia da Universidade Federal do Maranhão https://orcid.org/0000-0002-2759-1408
Wherveson de Araújo Ramos Enfermeiro; Mestre pelo Programa de Pós-Graduação em Saúde e Tecnologia da Universidade Federal do Maranhão https://orcid.org/0000-0002-8741-2686

DOI:

https://doi.org/10.36489/saudecoletiva.2025v16i99p16838-16851

Keywords:

Drug-Related Side Effects and Adverse Reactions, Pediatric

Abstract

OBJECTIVE: To identify the medications associated with adverse events in the pediatric population, as well as the main reactions involved. METHODOLOGY: An integrative literature review conducted in March 2024, using the MEDLINE, LILACS, and SciELO databases. The guiding question was: "Which medications are associated with adverse events in the pediatric population?" RESULTS: Studies published between 2019 and 2023 investigated adverse drug reactions in pediatric patients. Antibiotics were the most frequently associated with adverse reactions, with ceftriaxone and amoxicillin being the most notable. The most common reactions included rash, diarrhea, and nausea/vomiting. Additionally, more severe reactions such as toxic epidermal necrolysis and acute renal failure were also reported. CONCLUSION: Adverse drug reactions in children represent a public health concern, as they can lead to severe complications. Therefore, rigorous monitoring, effective reporting systems, and further research on pediatric drug safety are essential.

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